Nanobubbles Deliver Targeted Cancer Drugs Using Ultrasound

To achieve the twofold imaging exam, engineers in Dr. Zhu's lab added NIR sensors to an ultrasound transducer, create a hand-held probe experienced of acquire both ultrasound images and light waves. The collected images and optical background were then process using a computer algorithm.

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Nanobubbles packed with the chemotherapy drug doxorubicin be inject into mice. The froth accumulate in the tumors, where on earth they dual to gel larger "microbubbles." When given away to ultrasound, the bubbles generate echo, which made it probable to image the tumor. The moment activeness from the ultrasound pop the bubbles, releasing the drug. In mice treat together with this method, the nanobubbles were more potent at blocking tumor expansion than other nanoparticle delivery method.

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